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Expertise of the month

May 30, 2023

Expertise of the month: Strong support to...

Events

May 25, 2023

The SpiroTeam will be in Boston, MA

Literature

May 03, 2023

Our article with Prof. Kevin Brown (University...

Expertise of the month

Apr 28, 2023

Expertise of the month: Libraries of sp<sup>3</sup>-rich...

Events

Apr 13, 2023

Biotech Networking Event at SpiroChem's facilities

Conferences

Mar 14, 2023

SpiroChem @ 2023 RNA Leaders Europe Congress

Events

Mar 06, 2023

Biotech Networking Event at SpiroChem's facilities (in...

Expertise of the month

Feb 28, 2023

Expertise of the month: Structure identification of...

Conferences

Jan 26, 2023

SpiroChem @ the 16th Winter Conference on...

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Discovery
Process R&D
Fully Integrated Services
Technology
Resources
Careers
About

Get in touch

contact@spirochem.com +41 61 685 9500 Follow us

Informations

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Impressum

https://tools.google.com/dlpage/gaoptout
https://allaboutcookies.org/

Stay Connected

Stay inspired with our newsletter subscription, keeping you informed on new concepts, products, solutions & more.

Medicinal Chemistry

Our Mission: Accelerate your project!

Typically : 1-6 chemists

Duration : 3-12+ months

Excellence in chemistry
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Full MedChem programs or Support for a specific phase:

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Bioisosteric replacement strategies

Properties Optimization
Back-up programs
IP Evaluation
Patent Filing

Hit Validation
Hit/Fragment Expansion
Hit-to-Lead
Lead Optimization
SAR Elucidation

Bioisosteric replacement strategies
Properties Optimization
Back-up programs
IP Evaluation
Patent Filing

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MedChem Enabling Platforms

Our Mission: Explore new chemical space for you

Typically : 2-5 chemists

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Fragment Libraries

Our Mission: Address unexplored chemical space and diversity

+700 molecules in stock
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Conformationally restricted structures
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DEL Scaffolds

Our Mission : Offer exclusive scaffolds

Bi- and tri-functionalized scaffolds
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Vectors : COOH, CHO, Aryl halides, Nboc, Nfmoc, boronates

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Our Mission: Design and implement de novo synthetic routes

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SpiroKits

The must-have medicinal chemistry toolbox designed to:

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Catalog

Our mission: Accelerate your R&D

+13 000 molecules
Innovative building blocks
Purity > 95%
Milligram to hundred gram scale
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Consulting

Our mission: Share our knowledge

Literature analysis
Analysis of SAR results and proposals
Strategy proposals for ADME optimization
Retrosynthetic analysis
Route scouting proposals
Patent gap analysis
Support for patent filing

*hourly rate, daily rate or project-based fee

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Computational Chemistry

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