Literature

Submit
request

REQUEST A QUOTE

Enter your contact information

Search

Enter what you are looking for

Search by keyword.

Search*

Discovery
Process R&D
Fully integrated services
- Our expert partner network
- Consulting
Technology
Resources
Careers
About

Discovery
Discovery
Process R&D
Process R&D
Fully integrated services
Fully integrated services
- Our expert partner network
- Consulting
Technology
Technology
Resources
Resources
Careers
About
About

All Press Releases

Press Releases
COVID-19 Statement
SpiroTeam
New Products & Concept
Events, conferences and webinars
Events
Conferences
Blog
Literature
Expertise of the month
Reach the Summit
Newsletter
SpiroChem Collections
Video

Literature

Feb 15, 2024

SpiroChem’s Macrocycle Library delivers clinical...

Literature

May 03, 2023

Our article with Prof. Kevin...

Literature

Jun 09, 2022

Strain-Release [2π + 2σ] Cycloadditions...

Literature

Oct 08, 2021

SpiroChem featured in Comprehensive Heterocyclic...

One team
many solutions

Careers

In our culturally diverse environment, characterized by a high ratio of PhD chemists, success is measured based on the efficiency and quality of deliveries and the overall performance of the team.

open positions

Discovery
Process R&D
Fully Integrated Services
Technology
Resources
Careers
About

Get in touch

contact@spirochem.com +41 61 685 9500 Follow us

Informations

Terms & Conditions

Impressum

https://tools.google.com/dlpage/gaoptout
https://allaboutcookies.org/

Stay Connected

Stay inspired with our newsletter subscription, keeping you informed on new concepts, products, solutions & more.

web by kara5.

Discovery
Process R&D
Fully Integrated Services
Technology
Resources
Careers
About

Get in touch

contact@spirochem.com +41 61 685 9500 Follow us

Informations

Terms & Conditions

Impressum

https://tools.google.com/dlpage/gaoptout
https://allaboutcookies.org/

Stay Connected

Stay inspired with our newsletter subscription, keeping you informed on new concepts, products, solutions & more.

Medicinal Chemistry

Our Mission: Accelerate your project!

Typically : 1-6 chemists

Duration : 3-12+ months

Excellence in chemistry
Creative drug design
Solution and productivity driven
Uncompromised quality

Full MedChem programs or Support for a specific phase:

Hit Validation
Hit/Fragment Expansion
Hit-to-Lead

Lead Optimization
SAR Elucidation
Bioisosteric replacement strategies

Properties Optimization
Back-up programs
IP Evaluation
Patent Filing

Hit Validation
Hit/Fragment Expansion
Hit-to-Lead
Lead Optimization
SAR Elucidation

Bioisosteric replacement strategies
Properties Optimization
Back-up programs
IP Evaluation
Patent Filing

discover more

MedChem Enabling Platforms

Our Mission: Explore new chemical space for you

Typically : 2-5 chemists

Duration : 3-12+ months

Opening of new exit vectors
Late-stage functionalization
Synthesis tractability
Unleashed design

discover more

Fragment Libraries

Our Mission: Address unexplored chemical space and diversity

+700 molecules in stock
Unique design
High sp³ content
Conformationally restricted structures
Scale-up and straightforward analoging guaranteed

discover more

DEL Scaffolds

Our Mission : Offer exclusive scaffolds

Bi- and tri-functionalized scaffolds
Uncharted chemical space
Unique dihedral angles covered
Orthogonal protecting groups
Vectors : COOH, CHO, Aryl halides, Nboc, Nfmoc, boronates

discover more

Route Scouting

Our Mission: Design and implement de novo synthetic routes

Typically: 1-3 chemists

Duration: 3-6+ months

De novo design of synthetic routes to target molecules
Trouble-shooting
Development of efficient in-process controls
Stress test, robustness check
Technology transfer package

discover more

SpiroKits

The must-have medicinal chemistry toolbox designed to:

Provide medchem turnkey solutions
Accelerate projects
Foster chemical space exploration
Support novelty

discover more

Catalog

Our mission: Accelerate your R&D

+13 000 molecules
Innovative building blocks
Purity > 95%
Milligram to hundred gram scale
Short delivery time

discover more

Consulting

Our mission: Share our knowledge

Literature analysis
Analysis of SAR results and proposals
Strategy proposals for ADME optimization
Retrosynthetic analysis
Route scouting proposals
Patent gap analysis
Support for patent filing

*hourly rate, daily rate or project-based fee

discover more

Computational Chemistry

Quis sint minim labore velit qui dolor. Non ea esse

Quis sint minim labore velit qui dolor. Non ea esse ad cillum sint aute dolor. Cillum veniam fugiat i

d et aliquip aute duis fugiat reprehenderit eiusmod.Quis sint m

Excepteur nisi ex commodo tempor pariatur sunt incididunt laborum. Veniam laborum ex irure exercitation voluptate ipsum dolore sunt commodo. Magna pariatur aute nostrud velit dolor aute ut sunt anim tempor dolor culpa amet. Ut adi

discover more