Adrian holds a PhD in Organic Chemistry from the University of Illinois at Chicago, obtained in 1991, followed by postdoctoral work with William P. Jencks at Brandeis University.
He spent more than a decade at Biogen where he contributed to various successful drug and clinical candidate projects involving biopharmaceuticals and small molecules. As a member of the company’s senior research leadership, he held seats on the R&D Committee (governing committee for Biogen’s 800-person R&D organization), Drug Discovery Core Management Team, Preclinical Development Team, Oncology R&D Committee, Immunology Research Committee, and Neurology Research Committee.
Since 2008, Adrian is a Professor of Chemistry at Boston University. At the Whitty Group, the primary research focus lies in discovering novel methods to impede protein-protein interactions utilizing small molecules, particularly through unconventional techniques like synthetic macrocycles and targeted covalent inhibitors. Additionally, they investigate the activation and signaling mechanisms of growth factor receptors.