About Us

A pioneering research partner

SpiroChem is a pioneering research partner driving innovation across the drug discovery and process R&D chemistry value chains.

Our world-class and dynamic team provides expertise based on a deep, collective knowledge base and the most advanced technology platforms on the market.

We provide advisory, reporting, and peace of mind that rapidly advances your research and regulatory milestones for both complex chemistry challenges and simpler molecules. SpiroChem offers fully integrated discovery services within our high-quality trusted research partner network, extending from medicinal chemistry into biology and guiding you from hit validation through lead optimisation to early process R&D.

Founded in 2011 and headquartered in Basel, Switzerland, SpiroChem has robust presence in proximity to key life science hubs, including a second R&D site in Montreal, Canada.

Our success lies in our ability to innovatively problem-solve with excellent communication and transparency. Our dedicated experts work as an extension of your team, bringing enthusiasm, creativity, and competency to every challenge, also leveraging SpiroChem’s collective knowhow - the SpiroBrain.

We take immense pride in our exceptionally high success rate that defies traditional market standards. The proof is in the feedback we receive from our industry customers and academic partners, consistently validating our position as best-in-class chemistry contract research organisation in the industry.

About us

01 How we work

SpiroChem is committed to providing clients with innovative solutions. We deliver the most robust science and peace of mind to our partners, both big and small, so they can focus on advancing their research program.

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Learn about SpiroChem, a pioneering research partner in drug discovery and process R&D, driving innovation.

02 The SpiroBrain

In many cases, the solutions to a specific chemistry challenge already exist, but nobody has connected the dots. We can and we do. Our passion for finding solutions takes us beyond our deep, collective knowledge base - which we call the ‘SpiroBrain.’

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03 Our advantage

We offer unparalleled quality solutions, delivered by an experienced world-class and dynamic team of experts. What sets us apart is our high productivity, with a consistently high success rate. We offer excellence in customer service and satisfaction and fully integrated services through our state-of-the-art transatlantic facilities and trusted global partner network.

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04 Our commitment

SpiroChem is unwavering in its commitment and drive to provide high-quality solutions. We offer you the ‘best chance of being successful’ and approach problems creatively to rapidly identify and address your true needs.

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05 Leadership team

We pride ourselves in delivering the most robust science and providing our customers with peace of mind - so they can focus on advancing their research programs.

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06 Our history

SpiroChem has pioneered innovation since 2011, having built a reputation for handling some of the most complex and challenging chemistry in the life sciences.

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Read what our valued clients and collaborators have to say

Testimonials

“Odyssey Therapeutics and SpiroChem collaborated on the synthesis of complex molecules and chemical libraries. The SpiroChem team was highly engaged as we defined the scope and aims of the work. SpiroChem worked quickly to evaluate multiple chemistries in parallel. Together, we defined the most productive and impactful path forward, executing on state-of-the-art, challenging synthetic transformations then quickly converting the results to library production. Our collaboration proceeded smoothly as SpiroChem scientists were model collaborators who communicated promptly, provided very efficient logistics, and exhibited a true can-do spirit. It was a pleasure to work with the SpiroChem team and we look forward to future work together.”

Natalie Dales, Chief of Research Operations and Portfolio Strategy Paul Gormisky, Senior Directory of Chemistry

“SpiroChem has played an instrumental part in Cellestia's drug discovery and development program, proving to be a reliable partner in delivering quality results in a timely manner. Within the framework of this collaboration, the team has spared no effort in meticulously executing the plan and actively participating in project meetings to contribute to the success of our medicinal chemistry efforts. SpiroChem's innovative and effective work helped us save CHF 0,5 million on the drug development program. I thoroughly enjoyed interacting with SpiroChem's team and CEO Dr. Thomas Fessard who always made himself person ally available to discuss the progress of our projects. Without any reservations, I would highly recommend SpiroChem to anyone looking for customized, innovative chemistry from a highly-in vested, strinkingly professional team.”

Rajwinder Lehal, Chief Scientific Officer

“We greatly appreciated our collaboration with SpiroChem, whose partnership allowed us to efficiently tackle complex synthetic challenges across our research programs. Their team combines deep expertise in cutting-edge synthetic and medicinal chemistry with a pragmatic approach to speed, quality, and problem solving. Beyond their direct scientific contributions, SpiroChem played a key coordinating role across our extended network of external CRO partners in China, India, and Ukraine. Their proactive management, technical oversight, and troubleshooting support have been instrumental in maintaining consistency, accelerating timelines, and ensuring scientific rigor throughout our global chemistry operations.”

Chris Oalmann, Vice President Medicinal Chemistry

“We highly value our collaboration with Spirochem, which enables us to address complex synthetic challenges across our pipeline programs. Their team demonstrates deep expertise in contemporary synthetic methodologies, and maintains rigorous attention to detail while aligning with our priorities for speed and efficiency. They additionally provide critical support to the Remix team by troubleshooting CRO-executed chemistry in China, contributing technical insight and actionable guidance through attendance at joint working group meetings.”

Benoit Moreau, Head of Medicinal Chemistry

“The SpiroChem team is an outstanding partner for NBE-Therapeutics for finding and optimizing complex synthesis routes for our linker-payloads. SpiroChem’s Team member’s ingenuity, efficiency and proactive attitude was key in finding novel avenues for synthesizing highly complex and also highly cytotoxic small molecules. Due to the close interactions between our teams, it feels like SpiroChem’s team is part of NBE.”

Ulf Grawunder COO & CDO of NBE-Therapeutics

"SpiroChem's expertise in synthetic chemistry, combined with their sense of urgency, make them an ideal partner for exploring new chemical space. Our critical collaboration on bicycloalkyl bioisosteres was published on ChemMedChem 2017 12 590. I have to highlight the ease of communication and the proactive role of SpiroChem, which we regularly experienced in our interactions. They are brilliant to work with, bother for standard synthesis or more demanding customized building blocks and I would recommend their services to any company seeking pragmatic, cutting-edge solutions."

Dr. Yves P. Auberson, executive director, Global Discovery Chemistry, Novartis Institutes for BioMedical Research and president of EEMC.

"It is with great joy that I am recommending SpiroChem based on the excellent job they did for us; Their high flexibility and reactivity to our fast-changing requests were outstanding. Furthermore, SpiroChem's excellent synthetic expertise enabled access to a key API, which we tested and proved to be the basis for the IP of a complete class of substances. Last but not least, I want to emphasize the outstanding and the fast delivery of the very detailed and precise final report with all the analytical documentation included.”

Dr. Peter C. Sennhenn, CEO of transMedChem Consulting

“We partnered with SpiroChem as part of a pilot structure-based drug design and medicinal chemistry campaign. The outcome was very successful! Despite time, budget and even technical constraints, the SpiroChem team promptly addressed our difficulties providing innovative and unexplored chemical solutions. We were able to design improved compounds, better understand the chemical biology of our project, and lay the foundation for further development campaigns. The SpiroChem Chemistry team has closely supported us through the entire process providing ideas and detailed clarification of the strategies undertaken. A great partnership that I am sure to be continued!”