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SpiroChem | News

  • Spirochem opens new state-of-the-art Services and R&D facilities in Basel, Switzerland and Strengthens Board of Directors

    spirochem_blog

     

    Spirochem opens new state-of-the-art Services and R&D facilities in Basel, Switzerland and Strengthens Board of Directors

    29 September 2017 - SpiroChem AG (“SpiroChem” or the “Company”), the Swiss fine chemicals company specialised in creating novel building blocks for use in drug discovery by its pharma and biotech partners, has today announced the relocation of its business to state-of-the-art facilities in Basel, Switzerland. The Company has also strengthened the Board with the appointment of Dr. Anthony Baxter to the Board of Directors with immediate effect.

    With a growing reputation as a trusted partner of choice in the life sciences industry and increasing demand for SpiroChem’s innovative products, the Company has relocated to new, enlarged facilities in the Rosental Area of Basel. Previously the Company was based at world-renowned ETH Zürich. This relocation is an exciting step for the Company as it provides an ideal location for SpiroChem to significantly expand its operations and foster collaborations with existing and new customers and partners. The laboratories and team are now fully operational in Basel.

    Dr Anthony Baxter joins the Company from Cyprotex plc, a leading supplier of DMPK services to the pharma and biotech community, where he held the position of CEO before its acquisition by Evotec AG in 2016 (£55m). Prior to this, Tony was the founding CEO of Argenta Discovery Ltd, a leading drug discovery services, and proprietary therapeutics company. In addition, Dr Baxter was CSO of Oxford Asymmetry International plc and helped build the business from an early stage company, to its flotation on the London Stock Exchange, and then to its eventual merger with Evotec AG in 2000 (£316m). Tony graduated from the University of Manchester in Salford, UK (MSc, PhD). Following this, Tony worked as a medicinal chemist with over 12 years senior level experience at GSK and Ciba-Geigy UK (now Novartis).

    Thomas Fessard, CEO of SpiroChem, commented:

    “We are excited to announce our move to state-of-the-art facilities in Basel. Our new set-up is ideal for interaction and collaborations with large and small organisations, providing flexibility and speed to solve problems, allowing our clients to focus on effectively designing the drugs of tomorrow. We will continue crafting innovative solutions for problems encountered in challenging and complex projects in the medicinal chemistry field. SpiroChem intends to become a key player in Basel’s vibrant, innovation-driven, life science scene, supporting our ambition to increase our portfolio of clients and recruit talented employees to join our growing, cutting-edge Company.

    Working with Tony will be a real boost. His industry experience and network will be invaluable as we continue to grow our portfolio of small, medium, and large pharmaceutical, agrochemical and life science clients worldwide.”

    Dr Baxter, Director, added:

    “I am delighted to join the Board of SpiroChem as the Company enters the next key phase of development on the road towards becoming a leading innovation and drug discovery partner to the pharmaceutical industry. I very much look forward to working with the team and leveraging my industry knowledge and experience as a chemist to SpiroChem’s full advantage.”

    Contacts

    SpiroChem AG  - Tel: +41 61 685 95 00
    Thomas Fessard, CEO

    FTI Consulting  - Tel: +44 20 3727 1000
    Mo Noonan / Anna Foster

    ________________

    SpiroChem AG is a Swiss Fine Chemical Company founded in 2011 as an ETH-Zürich spin-off (group of Prof. Erick Carreira). SpiroChem has established itself as a world-leader in the field of novel building blocks for drug discovery and the expert on bioisosteric switch strategies. We have a broad portfolio of clients across the biotech and pharmaceutical industry as well as world-leading fine chemical companies.

    SpiroChem drives the new molecule and synthesis innovation process, leading the way to new classes of molecules with highly attractive cost/benefit profiles due their intrinsic properties: 1) improved physico-chemical and pharmaco-kinetic properties and 2) chemical novelty allowing the generation of new intellectual property. The beneficial properties of SpiroChem’s compounds mean that our clients can optimize their drug candidates faster, therefore accelerating their drug discovery programs.

    With recognized excellence in drug design and proprietary process chemistry technologies, SpiroChem efforts have been recognized with several entrepreneurial awards. It is the recipient of two sizable Swiss government grants (KTI). The forward-thinking initiatives enable discovery and innovation within the framework of research collaborations with ETH-Zürich.

    Explore a new world of possibilities for innovation and discovery.

  • SpiroChem @ the EFMC-ASMC'17

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    EFMC-ASMC'17 - EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry

    Vienna, Austria - August 27-31, 2017

    SpiroChem - Booth #8

    SpiroChem will be participating at the 7th edition of the EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry (EFMC-ASMC ’17).

    We are happy to announce that SpiroChem’s CEO, Dr. Fessard, will be one of the speakers and will share his expertise on "Isosteric-Switch Strategies: New Concepts and Recent Advances" at the 7th edition of the EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry.

    Find out more about Dr. Thomas Fessard.

    Visit us at Booth #8 and do not hesitate to contact us to arrange a meeting.

    Nolwenn Daubin – Business Development and Marketing Manager

    Telephone: +41 44 633 7363

    Mobile phone: +41 79 102 4177

    E-mail: nolwenn.daubin@spirochem.com

  • SpiroChem @ the SCS Fall Meeting 2017

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    SCS Fall Meeting 2017

    Bern, Switzerland - August 21-22, 2017

    University of Bern

    SpiroChem - Booth #12

    SpiroChem will be exhibiting at the SCS Fall Meeting 2017, in Bern, Switzerland.

    Visit us at Booth #12 and do not hesitate to contact us to arrange a meeting.

    Teuta Hana Hajdari

    Telephone: +41 61 685 95 00

    Mobile phone: +41 76 80 10 988

    E-mail: teuta.hajdari@spirochem.com

    Nolwenn Daubin – Business Development and Marketing Manager

    Telephone: +41 44 633 7363

    Mobile phone: +41 79 10 24 177

    E-mail: nolwenn.daubin@spirochem.com

  • SpiroChem @ the 254th American Chemical Society (ACS)

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    254th American Chemical Society (ACS) - National Meeting & Exposition

    Chemistry’s Impact on the Global Economy

    August 20-24, 2017 - Washington, DC

    SpiroChem - Booth # 721

    SpiroChem will be exhibiting in Washington, DC on August 20-24, 2017 for the 254th American Chemical Society, National Meeting & Exposition (ACS Fall 2017).

    We will be available on the exhibition floor (Booth #721) to answer your questions about our products and services. Let's discuss chemistry and the possible ways in which we can support and inspire you in overcoming your projects’ challenges.

    At SpiroChem it is all about chemists interacting with fellow chemists!

    SpiroChem AG: Tailor-made molecules to design the drugs of tomorrow

    Visit our Booth #721 and do not hesitate to contact us to arrange a meeting.

    Nolwenn Daubin – Business Development and Marketing Manager

    Telephone: +41 44 633 7363

    E-mail: nolwenn.daubin@spirochem.com

  • Welcome at RICT 2017 | SpiroChem - Booth #15

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    SpiroChem @ The 53rd International Conference on Medicinal Chemistry (RICT)

    July 5th-7th, 2017 - Toulouse, Occitanie, France

    Our SpiroTeam is participating at the 53rd International Conference on Medicinal Chemistry, in Toulouse, France.

    Welcome and visit our Booth #15 and do not hesitate to contact us to arrange a meeting.

    Contact: Nolwenn Daubin – Business Development and Marketing Manager

    Telephone: +41 44 633 7363

    E-mail: nolwenn.daubin@spirochem.com

  • SpiroChem @ RICT 2017 - The 53rd International Conference on Medicinal Chemistry

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    The 53rd International Conference on Medicinal Chemistry (RICT)

    July 5th-7th, 2017 - Toulouse, Occitanie, France

    We announce SpiroChem’s participation at the 53rd International Conference on Medicinal Chemistry, in Toulouse, France.

    Please visit our Booth #15 and do not hesitate to contact us to arrange a meeting.

    Contact: Nolwenn Daubin – Business Development and Marketing Manager

    Telephone: +41 44 633 7363

    E-mail: nolwenn.daubin@spirochem.com

  • 7e Symposium Francophone de Synthèse Totale

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    7e Symposium Francophone de Synthèse Totale

    June 1st - June 2nd, 2017 | Laboratory of the Linear Accelerator (Orsay)

    SpiroChem’s CEO, Dr. Thomas Fessard, will be one of the two industrial speakers at the 7th edition of the Francophone Symposium Total Synthesis (SFST7).

    The Symposium will be held at the Laboratory of the Linear Accelerator (Orsay) from Thursday, June 1st, until Friday, June 2nd, 2017.

    The aim of this congress is to promote the emerging French hub of total synthesis, by bringing together various participants in this discipline and emphasizing the young researchers and innovators.

    Find out more about Dr. Thomas Fessard.

    And do not hesitate to contact us in order to arrange a meeting.

    Nolwenn Daubin – Business Development and Marketing Manager

    Telephone: +41 44 633 7363

    Mobile phone:  +41 79 102 4177

    E-mail: nolwenn.daubin@spirochem.com

  • SpiroChem @ Chemspec Europe 2017

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    32nd International Exhibition for Fine and Speciality Chemicals (Chemspec Europe 2017)

    May 31st  - June 1st, 2017 | Münich, Germany

    http://www.chemspeceurope.com/en/

    SpiroChem team will be attending the 32nd International Exhibition for Fine and Speciality Chemicals on May 31st, 2017 in Münich, Germany.

    Do not hesitate to contact us to arrange a meeting.

    Nolwenn Daubin – Business Development and Marketing Manager

    Telephone: +41 44 633 7363

    Mobile phone:  +41 79 102 4177

    E-mail: nolwenn.daubin@spirochem.com

  • Improving Nonspecific Binding and Solubility: BicycloalkylGroups and Cubanes as para-Phenyl Bioisosteres | ChemMedChem Article - SpiroChem

    chemmedchem

     

    "Dear Colleagues, check out a recent article in ChemMedChem (DOI: 10.1002/cmdc.201700082) by scientists at Novartis (Basel, Switzerland) on the impact of 2D->3D isosteric switches on non-specific binding and solubility. SpiroChem is proud to have contributed to this project with Novartis. This shows the yet underestimated potential of bicyclo[1.1.1]pentanes and cubanes in drug discovery."

    About SpiroChem:

    SpiroChem is the world-leading supplier of bicyclo[1.1.1]pentanes and cubanes and a specialist on bio-isosteric strategies with the largest portfolio of solutions for ADME optimization, scaffold-hopping and chemical space exploration.

  • Process Chemist – Organic Synthesis

    We Are Hiring! Process Chemist – Organic Synthesis

    laboratory

     

    Basel - CH 4057
    Starting date: The position is open starting June 1st, 2017 or afterward upon agreement.

    Position summary:

    In this position, you will design, plan and perform scientific experiments/plant activities for chemical synthesis development, route scouting, optimization and scale-up (up to Kg scale). You will generate and evaluate data, interpret and report results, draw conclusions and write reports. Additionally, you will actively participate in project management. The successful candidate is holding a Master or PhD degree in synthetic organic chemistry and has > 3 years of practical industry experience in chemical process R&D and manufacturing. Specifically, you will provide support to the laboratory department by performing and/or coordinating a variety of laboratory processes:

    • Perform multi-step small molecule organic synthesis experimentation (mg to Kg scale).
    • Develop / optimize synthetic routes for scalable manufacturing from customer packages.
    • Provide technical leadership as subject matter expert for projects.
    • Manage process optimization, process review, and investigation brainstorm activities.
    • Provide mentorship to junior team members.

    Qualifications

    Master or PhD degree in synthetic organic chemistry. Demonstrated laboratory skills and technical expertise in the field of process chemistry R&D (scientific publications / patent applications). > 3 years industrial experience. Experience in flow-chemistry and photo-chemistry would be an advantage. GMP experience may also be of advantage. Versatility in common IT applications (Microsoft office). Proficient use of scientific databases (SciFinder, Reaxys), chemistry softwares (ChemDraw, ChemInventory) and electronic laboratory journal (E-Notebook). Excellent organizational skills and accuracy in experimental documentation. Good communications skills and fluency in English.  Knowledge of German may be of advantage. Teamwork/Interpersonal skills. Ability to manage multiple projects efficiently.

    What SpiroChem offers:

    - A stimulating working environment in a fast-growing high-tech SME, with challenging projects and exciting internal R&D. - The possibility for development and advancement within our dynamic organization.

    How to contact us:

    Send your CV including references and cover letter to Dr. Thomas Fessard at jobs@spirochem.com

    About SpiroChem:

    Founded in 2011, SpiroChem AG is a Swiss fine chemicals company, based in Basel, Switzerland. We are specialized in the design, synthesis, production and commercialization of innovative building blocks for Drug Discovery. With cutting-edge know-how in drug design and proprietary process chemistry technologies, SpiroChem has become the ideal collaboration partner for large, medium and small pharmaceutical, agrochemical and life science companies. Our clients are located worldwide, including 16 of the top 20 pharma companies.

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