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SpiroChem | News

  • SpiroChem @ RICT 2017 - The 53rd International Conference on Medicinal Chemistry

    blog

     

    The 53rd International Conference on Medicinal Chemistry (RICT)

    July 5th-7th, 2017 - Toulouse, Occitanie, France

    We announce SpiroChem’s participation at the 53rd International Conference on Medicinal Chemistry, in Toulouse, France.

    Please visit our Booth #15 and do not hesitate to contact us to arrange a meeting.

    Contact: Nolwenn Daubin – Business Development and Marketing Manager

    Telephone: +41 44 633 7363

    E-mail: nolwenn.daubin@spirochem.com

  • 7e Symposium Francophone de Synthèse Totale

    blog

     

    7e Symposium Francophone de Synthèse Totale

    June 1st - June 2nd, 2017 | Laboratory of the Linear Accelerator (Orsay)

    SpiroChem’s CEO, Dr. Thomas Fessard, will be one of the two industrial speakers at the 7th edition of the Francophone Symposium Total Synthesis (SFST7).

    The Symposium will be held at the Laboratory of the Linear Accelerator (Orsay) from Thursday, June 1st, until Friday, June 2nd, 2017.

    The aim of this congress is to promote the emerging French hub of total synthesis, by bringing together various participants in this discipline and emphasizing the young researchers and innovators.

    Find out more about Dr. Thomas Fessard.

    And do not hesitate to contact us in order to arrange a meeting.

    Nolwenn Daubin – Business Development and Marketing Manager

    Telephone: +41 44 633 7363

    Mobile phone:  +41 79 102 4177

    E-mail: nolwenn.daubin@spirochem.com

  • SpiroChem @ Chemspec Europe 2017

    Spec chem

     

    32nd International Exhibition for Fine and Speciality Chemicals (Chemspec Europe 2017)

    May 31st  - June 1st, 2017 | Münich, Germany

    http://www.chemspeceurope.com/en/

    SpiroChem team will be attending the 32nd International Exhibition for Fine and Speciality Chemicals on May 31st, 2017 in Münich, Germany.

    Do not hesitate to contact us to arrange a meeting.

    Nolwenn Daubin – Business Development and Marketing Manager

    Telephone: +41 44 633 7363

    Mobile phone:  +41 79 102 4177

    E-mail: nolwenn.daubin@spirochem.com

  • Improving Nonspecific Binding and Solubility: BicycloalkylGroups and Cubanes as para-Phenyl Bioisosteres | ChemMedChem Article - SpiroChem

    chemmedchem

     

    "Dear Colleagues, check out a recent article in ChemMedChem (DOI: 10.1002/cmdc.201700082) by scientists at Novartis (Basel, Switzerland) on the impact of 2D->3D isosteric switches on non-specific binding and solubility. SpiroChem is proud to have contributed to this project with Novartis. This shows the yet underestimated potential of bicyclo[1.1.1]pentanes and cubanes in drug discovery."

    About SpiroChem:

    SpiroChem is the world-leading supplier of bicyclo[1.1.1]pentanes and cubanes and a specialist on bio-isosteric strategies with the largest portfolio of solutions for ADME optimization, scaffold-hopping and chemical space exploration.

  • Process Chemist – Organic Synthesis

    We Are Hiring! Process Chemist – Organic Synthesis

    laboratory

     

    Basel - CH 4057
    Starting date: The position is open starting June 1st, 2017 or afterward upon agreement.

    Position summary:

    In this position, you will design, plan and perform scientific experiments/plant activities for chemical synthesis development, route scouting, optimization and scale-up (up to Kg scale). You will generate and evaluate data, interpret and report results, draw conclusions and write reports. Additionally, you will actively participate in project management. The successful candidate is holding a Master or PhD degree in synthetic organic chemistry and has > 3 years of practical industry experience in chemical process R&D and manufacturing. Specifically, you will provide support to the laboratory department by performing and/or coordinating a variety of laboratory processes:

    • Perform multi-step small molecule organic synthesis experimentation (mg to Kg scale).
    • Develop / optimize synthetic routes for scalable manufacturing from customer packages.
    • Provide technical leadership as subject matter expert for projects.
    • Manage process optimization, process review, and investigation brainstorm activities.
    • Provide mentorship to junior team members.

    Qualifications

    Master or PhD degree in synthetic organic chemistry. Demonstrated laboratory skills and technical expertise in the field of process chemistry R&D (scientific publications / patent applications). > 3 years industrial experience. Experience in flow-chemistry and photo-chemistry would be an advantage. GMP experience may also be of advantage. Versatility in common IT applications (Microsoft office). Proficient use of scientific databases (SciFinder, Reaxys), chemistry softwares (ChemDraw, ChemInventory) and electronic laboratory journal (E-Notebook). Excellent organizational skills and accuracy in experimental documentation. Good communications skills and fluency in English.  Knowledge of German may be of advantage. Teamwork/Interpersonal skills. Ability to manage multiple projects efficiently.

    What SpiroChem offers:

    - A stimulating working environment in a fast-growing high-tech SME, with challenging projects and exciting internal R&D. - The possibility for development and advancement within our dynamic organization.

    How to contact us:

    Send your CV including references and cover letter to Dr. Thomas Fessard at jobs@spirochem.com

    About SpiroChem:

    Founded in 2011, SpiroChem AG is a Swiss fine chemicals company, based in Basel, Switzerland. We are specialized in the design, synthesis, production and commercialization of innovative building blocks for Drug Discovery. With cutting-edge know-how in drug design and proprietary process chemistry technologies, SpiroChem has become the ideal collaboration partner for large, medium and small pharmaceutical, agrochemical and life science companies. Our clients are located worldwide, including 16 of the top 20 pharma companies.

  • Laboratory Technician – Organic Chemistry

    We Are Hiring! Laboratory Technician – Organic Chemistry

    laboratory

    Basel - CH 4057
    Starting date: The position is open starting June 1st, 2017 or afterward upon agreement.

    Position summary:

    This position is to perform and document routine tasks related to sample processing and assays, standard laboratory methods and/or basic laboratory techniques, functions and equipment. To conduct specific procedures and tests both within and outside of the laboratory requiring the use of applied knowledge and practical chemistry skills. The successful candidate is holding a Bachelor or Master degree in synthetic organic chemistry or equivalent. Knowledge of modern chemical and analytical techniques is mandatory.

    Specifically, you will provide support to the laboratory department by performing and/or coordinating a variety of laboratory processes:

    - Register and prepare samples for general analytical testing (NMR and MS spectroscopy) through sample receiving, data entry, weighing, physical homogenization, and shipping (FedEx/DHL/UPS). - Manage the inventory of chemical reagents and catalog substances. - Operate basic laboratory equipment. - Synthesize and handle catalog substances. - Prepare (and assure accuracy of) standards, reagents, etc. needed for analyses. - Perform routine lab and department maintenance to keep area clean and orderly. - Order chemical reagents from suppliers.

    Qualifications

    Bachelor or Master chemistry degree in synthetic organic chemistry. Versatility in common IT applications (Microsoft office). Proficient use of scientific databases (SciFinder, Reaxys), chemistry softwares (ChemDraw, ChemInventory) and electronic laboratory journal (E-Notebook). Excellent organizational skills and accuracy in experimental documentation. Good communications skills and fluency in English and German are essential.

    What SpiroChem offers:

    - A stimulating working environment in a fast-growing high-tech SME, with challenging projects and exciting internal R&D. - The possibility for development and advancement within our dynamic organization.

    How to contact us:

    Send your CV including references and cover letter to Dr. Thomas Fessard at jobs@spirochem.com

    About SpiroChem:

    Founded in 2011, SpiroChem AG is a Swiss fine chemicals company, based in Basel, Switzerland. We are specialized in the design, synthesis, production and commercialization of innovative building blocks for Drug Discovery. With cutting-edge know-how in drug design and proprietary process chemistry technologies, SpiroChem has become the ideal collaboration partner for large, medium and small pharmaceutical, agrochemical and life science companies. Our clients are located worldwide, including 16 of the top 20 pharma companies.

  • Reunion of Carreira group alumni

    ACS-Carreira

     

    Reunion of Carreira group alumni:

    Prof. Corey Stephenson and Prof. Corinna Shindler from University of Michigan (USA), Prof. Jérôme Waser from EPF Lausanne (Switzerland), Dr. Thomas Fessard (CEO SpiroChem) and Prof. Carreira's academic grandchildren, the chemists of tomorrow!

  • SpiroCycles – Episode 2/2

    SpiroCycles – Episode 2/2 Conformationally Restricted Scaffolds


    spirocycles

    Over 1’000 SpiroCyclic derivatives available
    Beyond catalog products: Custom Synthesis & Diversification

    We are a world-leading company on chemical diversity and expansion of the chemical space, with many years of experience in the design and synthesis of novel spirocyclic fragments for drug discovery. Our long-term involvement in the field of SpiroCycles also allows us to design synthetic routes to new series that are fit for your applications and that will facilitate introduction of these new scaffolds in your molecules of interest.

    Do not hesitate contacting us, we will provide you with tailor-made solutions!

    Get Inspired with our Building Blocks to Create the Drugs of Tomorrow.

    Contact Us

  • SpiroCycles – Episode 1/2

    SpiroCycles Conformationally restricted (thio)morpholine/piperazine bioisosteres


    spirocycles

    Over 1’000 SpiroCyclic derivatives available
    Beyond catalog products: Custom Synthesis & Diversification

    We are a world-leading company on chemical diversity and expansion of the chemical space, with many years of experience in the design and synthesis of novel spirocyclic fragments for drug discovery. Our long-term involvement in the field of SpiroCycles also allows us to design synthetic routes to new series that are fit for your applications and that will facilitate introduction of these new scaffolds in your molecules of interest.

    Do not hesitate contacting us, we will provide you with tailor-made solutions!

    Get Inspired with our Building Blocks to Create the Drugs of Tomorrow.

    Contact Us

  • SpiroChem @ the ACS 2017

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    Meet SpiroChem during the 253rd ACS 2017 in San Francisco, California on April 2-4, 2017.

    Our SpiroChem team will be part of the 253rd American Chemical Society, National Meeting & Exposition and will be exhibiting in San Francisco, California on April 2-4, 2017.

    Exhibiting at the ACS 2017 this Spring will be another opportunity for us to interact with thousands of inspiring scientists and enthusiastic students who share our passion for chemistry.

    We will be available on the exhibition floor to answer your questions about our products and services. Let's talk about chemistry and see how we can help you face the challenges in your projects.

    At SpiroChem it is all about chemists interacting with fellow chemists!

    SpiroChem AG: Tailor-made molecules to design the drugs of tomorrow

    253rd ACS 2017, National Meeting & Exposition
          ACS 2017 - The world’s largest scientific society, organizes 2 national expositions, each year, in addition to their national meetings, each attracting over 14,000 chemical engineers, chemists, academicians, students and other professionals from the chemical industry to learn more about the cutting-edge technologies in the chemical field.  The Exposition is the hot spot to explore services and products from world-known companies from around the globe but also to investigate new trends, techniques and technologies such as laboratory equipment, hardware, software, publications, etc.  The ACS National Meetings are where professionals from the field of chemistry meet to share ideas and advance scientific and technical knowledge.

    What ACS wrote about SpiroChem SpiroChem AG is a Swiss CRO specialized in the design, synthesis and production of novel building blocks for use in drug discovery. With its unique repertoire of molecular fragments along with cutting-edge know-how in drug design & process chemistry, SpiroChem is the ideal collaboration partner for life science companies (Custom Synthesis & FTE services).

    SpiroChem expertise:
      • Bio-isosteric switch strategies
      • Conformational restriction and strained fragments and scaffolds
      • Chemical Diversity
      • Challenging chemistry
      • Problems solver: Ideal Partner for Sensitive/high-value projects
      • Pro-active: We set the trends
      • Small rings | Spirocycles | Bicyclo[x.y.z]alkanes | Peptidomimetics | Natural Products
    Product Categories:
      • Organic Chemistry
      • Custom Synthesis Services
      • Contract Research & Development Services
      • Fine Chemicals
      • Method Development & Optimization
      • Pharmaceutical Intermediates & Building Blocks
      • Photochemicals
      • Process Research Services
      • Scale-up Optimization
      • Scale-up Synthesis
      • And much more!

    If you are looking for expertise in isosteric replacement or in any of these chemical series, you are at the right place! SpiroChem is not only a catalog company, nor just a CRO. SpiroChem is your R&D partner to ACCELERATE YOUR INNOVATION!

    Additional Services:
        Additionally to the set of services SpiroChem already offer (from catalog products to custom synthesis services, feasibility studies and FTEs), we provide our clients with personalized services such as:

        • - supporting lead optimization programs to improve ADME properties of drug candidates
        • - entering into new chemical space, expanding your IP-portfolio and strengthening your IP protection

    Join us in San Francisco, California on April 2-4, 2017 for the 253rd American Chemical Society National Meeting & Exposition at the Moscone Center! Arrange a Meeting with us NOW!

    Dates : April 2-4, 2017

    Venue :  Moscone Center - San Francisco, CA

    Visit us on Booth #421 and arrange a meeting with us. We look forward to meeting you!

    Contact : Nolwenn Daubin – Business Development and Marketing Manager

    Telephone: +41 44 633 7363

    E-mail: nolwenn.daubin@spirochem.com

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