Virtual Library

Embark upon uncharted chemical space

SpiroSpace™ is a virtual library built upon SpiroChem knowledge.

It provides access to innovative drug-like sp3-rich compounds covering uncharted chemical space. Thanks to our in-house know-how, these compounds are diversified and tractable.

SpiroSpace^TM
Generation

SpiroSpace™ = 5.4 million molecules designed:

From selected SpiroChem & drug-like building blocks
Using 6 chemical reaction types
Arising from 2-step synthesis max

SpiroSpace™ compiles:

Drug-like molecules (Ro5 compliant)
Sp3-rich compounds with constrained conformations
Innovative scaffolds combinations

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Hit finding novel targets and IP space

SpiroSpace™ is dedicated to support hit finding with identification of novel drug-like hits, highly valuable starting points for MedChem programs, to explore novel targets and IP space.

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SpiroSpace^TM properties

Physicochemical property distributions demonstrate our unrivaled the SpiroSpace™ library.

By combining drug-like properties with sp3-enrichment and structurally complex 3D geometry, SpiroSpace™ molecules open new horizons for hit finding.

The physicochemical property distributions of the SpiroSpace library demonstrate the level of diversity they offer:

Get access to the full SpiroSpace™ molecule list.

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What our clients
say about us

With a wealth of experience in chemistry, SpiroChem offers unparalleled high-quality solutions supported by a world-class team.

Testimonials

“Odyssey Therapeutics and SpiroChem collaborated on the synthesis of complex molecules and chemical libraries. The SpiroChem team was highly engaged as we defined the scope and aims of the work. SpiroChem worked quickly to evaluate multiple chemistries in parallel. Together, we defined the most productive and impactful path forward, executing on state-of-the-art, challenging synthetic transformations then quickly converting the results to library production. Our collaboration proceeded smoothly as SpiroChem scientists were model collaborators who communicated promptly, provided very efficient logistics, and exhibited a true can-do spirit. It was a pleasure to work with the SpiroChem team and we look forward to future work together.”