Reshaping Flatland: Dearomative Methods for Rapid Construction of Valuable 3D Molecules

Reshaping Flatland: the story behind small rings and spirocycles

Reshaping Flatland: Methods to access novel 3D conformationally-restricted motifs: it’s all about efficiency

Reshaping Flatland: The principles of constraining lipophilicity, saturation and shape

Pushing boundaries: Photoinduced Assembly of C-N and C-C bonds

Pushing boundaries: New methodologies and enabling technologies to decorrelate structural complexity from synthetic accessibility

Pushing boundaries: Design of highly 3D libraries and case studies

Pushing boundaries: Break-it-to-Make-it Strategies for Chemical Synthesis Inspired by Complex Natural Products

No Strain, No Gain: Advances in the Synthesis and Design of New Classes of Strained Building Blocks

Pharmacophore-based Virtual Screening: Examples Using The New SpiroChem Libraries

The kinase-phosphatase mystery: a prolific and an underexplored target family