SpiroChem AG:
Rosental area, WRO-1047-3
Mattenstrasse 22
4058 Basel, Switzerland
Tel: + 41 61 685 95 00
E-mail: contact@spirochem.com
Swiss Discovery Sciences
Covalent targeting is playing an increasing role in medicinal chemistry and chemical biology. Covalent targeted inhibitors typically result from a structure-based design, starting with optimized reversible ligands that are then modified by the addition of a warhead to attack a proximal amino acid. More recently, different approaches, such as the fragment-based one, have emerged as alternative strategies.
Across many projects, SpiroChem has acquired experience in the synthesis of warheads targeting Cys, Cys/Lys, Lys/Tyr, Lys/Tyr/Ser.
Our computational and medicinal chemists are active in:
At SpiroChem, we’re using our knowledge to design innovative covalent fragments with high 3D diversity shape which improves pharmacophore coverage and solubility.
With 450 covalent fragments in stock, SpiroChem offers novel high-value starting points for your discovery projects.
All fragments are in stock and available as powder from 1mg.
At SpiroChem, we’re using our knowledge to design innovative covalent fragments with high 3D diversity shape which improves pharmacophore coverage and solubility.
With 450 covalent fragments in stock, SpiroChem offers novel high-value starting points for your discovery projects.
All fragments are in stock and available as powder from 1mg.
At SpiroChem, we’re using our knowledge to design innovative covalent fragments with high 3D diversity shape which improves pharmacophore coverage and solubility.
With 450 covalent fragments in stock, SpiroChem offers novel high-value starting points for your discovery projects.
All fragments are in stock and available as powder from 1mg.
At SpiroChem, we’re using our knowledge to design innovative covalent fragments with high 3D diversity shape which improves pharmacophore coverage and solubility.
With 450 covalent fragments in stock, SpiroChem offers novel high-value starting points for your discovery projects.
All fragments are in stock and available as powder from 1mg.
At SpiroChem, we’re using our knowledge to design innovative covalent fragments with high 3D diversity shape which improves pharmacophore coverage and solubility.
With 450 covalent fragments in stock, SpiroChem offers novel high-value starting points for your discovery projects.
All fragments are in stock and available as powder from 1mg.