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Mattenstrasse 24
4058 Basel, Switzerland


Tel: + 41 61 685 95 00
E-mail: contact@spirochem.com


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SpiroKit 5

Bicyclic diamines as piperazine surrogates

SpiroKit 5 is a smart selection of 41 monoBoc bicyclic diamines, valuable analogs and surrogates of piperazine which is one of the most commonly used building block in medicinal chemistry.

SpiroKit 5: Bicyclic diamines as piperazine surrogates

Why SpiroKit 5?

Replacing the piperazine ring with substituted, bridged, fused or spiro bicyclic diamines provides an opportunity to uniquely:

  • Tune the molecule geometry
  • Modulate the physicochemical properties
  • Secure the IP
  • Optimize the activity and the selectivity
  • Improve the ADME properties
SpiroKit 5: Bicyclic diamines as piperazine surrogates

Offered subsets

SpiroKit 5a : Substituted and bridged monoBoc piperazines

A selection of 14 substituted and bridged monoBoc piperazines with diversified tethers and spiro/fused rings as substituants.

Catalog ID Compounds Amount (each) Price (whole set)
SPK5a 14 100mg CHF 1.910 USD 2.090
250mg CHF 3.250 USD 3.490
500mg CHF 4.900 USD 5.390

A selection of 19 monoboc spirodiamines as piperazine surrogates

Catalog ID Compounds Amount (each) Price (whole set)
SPK5b 19 100mg CHF 2.500 USD 2.790
250mg CHF 4.250 USD 4.690
500mg CHF 6.370 USD 6.990

A selection of 8 monoboc fused diamines as piperazine surrogates

Catalog ID Compounds Amount (each) Price (whole set)
SPK5c 8 100mg CHF 1.910 USD 2.090
250mg CHF 3.250 USD 3.590
500mg CHF 4.870 USD 5.390
SpiroKit 5: Bicyclic diamines as piperazine surrogates

More Information

To receive more information about the SpiroKits, please contact Laurence Jung, PhD: laurence.jung@spirochem.com

SpiroKits

Other SpiroKits

SpiroKit 1

pKa-Tuned
Amines

SpiroKit 2

sp2 to sp3
Switch

SpiroKit 3

Constrained
Amino Acids

SpiroKit 4

Azaspiro[3.3]heptane derivatives

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