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29.03.2019

Molecule of the Week

Take a closer look at our NATURAL PRODUCTS

Available at SpiroChem

NATURAL PRODUCTS

Amaryllidaceae alkaloids:
(+)-pancratistatin, (+)-lycoricidine, (+)-narciclasine and novel synthetic analogs

Based on the isocarbosyril core.

Cytotoxic activity:

  • In vitro RNA antiviral activity
  • In vivo murine Japanese encephalitis
  • In vitro anti-microsporidium

Natural products available on gram scale and beyond
Large range of analogs can be made on demand
Tractable chemical space for Analoging and downstream SAR

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