SpiroChem AG:
Rosental area, WRO-1047-3
Mattenstrasse 24
4058 Basel, Switzerland


Tel: + 41 61 685 95 00
E-mail: contact@spirochem.com


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SpiroKits

How can you maximize the information/protection with a limited set of analogs? Our answer: SpiroKits!

For each important medchem motif, we have selected diverse sets of isosteric replacements. We offer focused library around a given motif, and possibility to synthesize the corresponding test compounds – from "mmol to gram" scale.

SpiroKits
SpiroKits

About SpiroKits™

At SpiroChem, our mission is to help medicinal chemists accelerate their projects and identify better drug candidates, faster! For this reason, ever since our inception, we have been working hard to develop new concepts and deliver solutions rather than merely “a gram of a chemical in a bottle”.

Easy to say, but how would we do that?

We reasoned that in many cases, Structure-Activity-Relationship (SAR) studies and ADME-optimization campaigns are time- and resource-consuming activities that, if done efficiently, can save you a lot of time (and troubles) downstream.

We have looked at the usual suspects, those motifs that you find in virtually EVERY project. You know them: morpholines, tert-butylamines, etc. They are not perfect, but you kept them as long as you could, because they were familiar. Although not perfect, they serve a purpose … for the time being. But there comes a time when you have no choice, and you will have to select this development candidate. Now is the time to ask yourself the following questions: how can I maximize the information/protection with a limited set of analogs? Our answer: SpiroKits!

For each important medchem motif, we have selected diverse sets of isosteric replacements for each of these and you can purchase this focused library around a given motif, synthesize the corresponding test compounds and test them! You can decide how much you need. 100mg? 1g? 2.47 mmol? Just tell us how we should pack it and we will prepare it for you.

Furthermore, if you need support in the downstream chemistry, we are here to help, whether it is to develop a late-stage introduction strategy or synthesize further sub-series of some of these examples. And if you need a special SpiroKit to cover a certain topic or answer a special question, we can design it with you!

SpiroKits

Let’s work together

Don’t wait any longer! We will be happy to discuss this further with you and help you accelerate your projects.

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