SpiroChem AG:
Rosental area, WRO-1047-3
Mattenstrasse 22
4058 Basel, Switzerland

Tel: + 41 61 685 95 00
E-mail: contact@spirochem.com


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Expertise of the month: ADC chemistry
Jun 29 2021

Expertise of the month

Expertise of the month: ADC chemistry


Our goal: escape from PEGLand!

By introducing compact conformationally restricted sp3-rich motifs, we design and prepare linkers which:

  • Balance the low solubility of payloads
  • Reduce the flexibility of the mAbs-payload complex
  • Enable to tune the length and orientation of the mAbs-payload complex
  • Secure your IP

Highly Potent Small Molecules Capabilities

A specially equipped lab enables us to work with payloads both for discovery (MedChem) and process (Route Optimization to get access to high-potent molecules). Our expertise in natural product synthesis is an asset to accelerate the project.


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