SpiroChem AG:
Rosental area, WRO-1047-3
Mattenstrasse 22
4058 Basel, Switzerland


Tel: + 41 61 685 95 00
E-mail: contact@spirochem.com


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Oct 2023

Reach the Summit

Climb to the summit with SpiroChem


Camp 4: Unlocking access to novel medicines

SpiroChem is committed to foster your Medicinal Chemistry programs either by supporting you from hit identification to pre-clinical candidate selection or by being involved in very specific phase(s) of your project.

We are involved in programs across different therapeutic areas and target families from small molecules to bifunctional molecules and macrocycles.

With two dedicated labs, we can also handle high-potent molecules and support ADC program by designing and synthesizing novel linker-payload complexes.

Thanks to a team of 100+ highly skilled scientists (65% PhDs, 35% MScs), strong management and the use of Enabling Technologies, SpiroChem tackles, challenges and brings creativity, innovation and productivity to your projects.

SpiroChem performs fast iterative optimization cycles combining:

CompChem Expertise
  • Pharmacophore-based screenings
  • High-throughput docking
  • Fragment-based approach
  • Scaffold-hopping
  • 3D Drug Design
  • Fragment-based approach
  • Proprietary virtual Libraries
  • Bio Switcher algorithm
Medicinal Chemistry Expertise
  • SAR & Early ADME data analysis
  • Properties optimization/fine-tuning
  • Bioisosteric replacement strategies
  • Novel chemical space exploration
  • IP evaluation / securing
  • Patent exempflication
Unrivalled Synthetic Skills
  • In-house Enabling Technologies: Photochemistry/Photoredox, Flow chemistry, Electrochemistry, Biocatalysis
  • Late-stage functionalization
  • New exit vector opening
  • Focused library preparation
  • Proprietary chemistry

We will be happy to support your projects.
For more information, please contact Laurence Jung at laurence.jung@spirochem.com

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