The incorporation of four-membered heterocycles into druglike scaffolds provides an opportunity to uniquely tune the physicochemical and biochemical properties of the parent compound. Moreover, these structures allow the exploration of novel chemical space.
A selection of 2-azaspiro[3.3]heptane derivatives with diversified substituants in position 6 as piperidine surrogates.
Catalog ID | Compounds | Amount (each) | Price | |
---|---|---|---|---|
SPK4a | 8 | 100mg | CHF 1.470 | USD 1.640 |
250mg | CHF 2.500 | USD 2.790 | ||
500mg | CHF 4.150 | USD 4.640 | ||
1000mg | CHF 6.220 | USD 6.960 |
A selection of 9 N-Boc protected 2-azaspiro[3.3]heptane derivatives with an handle in position 6 or 5.
Catalog ID | Compounds | Amount (each) | Price | |
---|---|---|---|---|
SPK4b | 9 | 100mg | CHF 2.310 | USD 2.580 |
250mg | CHF 3.920 | USD 4.380 | ||
500mg | CHF 6.660 | USD 7.450 | ||
1000mg | CHF 9.990 | USD 11.180 |
A selection of 6 diazaspiro[3.3]heptane derivatives as piperazine surrogates.
Catalog ID | Compounds | Amount (each) | Price | |
---|---|---|---|---|
SPK4c | 6 | 100mg | CHF 1.680 | USD 1.870 |
250mg | CHF 2.850 | USD 3.180 | ||
500mg | CHF 4.250 | USD 4.750 | ||
1000mg | CHF 6.350 | USD 7.100 |
A selection of oxo-, thia- and thia dioxide- azaspiro[3.3]heptane derivatives as morpholine, thiomorpholine and thiomorpholine dioxine surrogates.
Catalog ID | Compounds | Amount (each) | Price | |
---|---|---|---|---|
SPK4d | 7 | 100mg | CHF 1.680 | USD 1.870 |
250mg | CHF 2.850 | USD 3.180 | ||
500mg | CHF 4.250 | USD 4.750 | ||
1000mg | CHF 6.350 | USD 7.100 |
To receive more information about the SpiroKits, please contact Laurence Jung, PhD: laurence.jung@spirochem.com