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Azaspiro[3.3]heptane derivatives
SpiroKit 4: Azaspiro[3.3]heptane derivatives

Why SpiroKit 4?

The incorporation of four-membered heterocycles into druglike scaffolds provides an opportunity to uniquely tune the physicochemical and biochemical properties of the parent compound. Moreover, these structures allow the exploration of novel chemical space.

SpiroKit 4: Azaspiro[3.3]heptane derivatives

Offered subsets

SPIROKIT 4a: Substituted piperidine surrogates

A selection of 2-azaspiro[3.3]heptane derivatives with diversified substituants in position 6 as piperidine surrogates.

Catalog ID Compounds Amount (each) Price
SPK4a 8 100mg CHF 1.470 USD 1.640
250mg CHF 2.500 USD 2.790
500mg CHF 4.150 USD 4.640
1000mg CHF 6.220 USD 6.960

A selection of 9 N-Boc protected 2-azaspiro[3.3]heptane derivatives with an handle in position 6 or 5.

Catalog ID Compounds Amount (each) Price
SPK4b 9 100mg CHF 2.310 USD 2.580
250mg CHF 3.920 USD 4.380
500mg CHF 6.660 USD 7.450
1000mg CHF 9.990 USD 11.180

A selection of 6 diazaspiro[3.3]heptane derivatives as piperazine surrogates.

Catalog ID Compounds Amount (each) Price
SPK4c 6 100mg CHF 1.680 USD 1.870
250mg CHF 2.850 USD 3.180
500mg CHF 4.250 USD 4.750
1000mg CHF 6.350 USD 7.100

A selection of oxo-, thia- and thia dioxide- azaspiro[3.3]heptane derivatives as morpholine, thiomorpholine and thiomorpholine dioxine surrogates.

Catalog ID Compounds Amount (each) Price
SPK4d 7 100mg CHF 1.680 USD 1.870
250mg CHF 2.850 USD 3.180
500mg CHF 4.250 USD 4.750
1000mg CHF 6.350 USD 7.100
SpiroKit 4: Azaspiro[3.3]heptane derivatives

More Information

To receive more information about the SpiroKits, please contact Laurence Jung, PhD: laurence.jung@spirochem.com

SpiroKits

Other SpiroKits

SpiroKit 1

pKa-Tuned
Amines

SpiroKit 2

sp2 to sp3
Switch

SpiroKit 3

Constrained
Amino Acids

SpiroKit 5

BCP & Cubane
Systems

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