SpiroChem AG:
Rosental area, WRO-1047-3
Mattenstrasse 24
4058 Basel, Switzerland
Tel: + 41 61 685 95 00
E-mail: contact@spirochem.com
Swiss Fine Chemicals
SpiroChem AG:
Rosental area, WRO-1047-3
Mattenstrasse 24
4058 Basel, Switzerland
Tel: + 41 61 685 95 00
E-mail: contact@spirochem.com
Swiss Fine Chemicals
Whether during hit evolution, hit-to-lead or lead optimization phase, the ability to rapidly and efficiently explore each position on the structure of interest allows for more rapid optimization. We offer :
SpiroChem chemists are used to serve as the A-team of chemistry for larger groups of chemists, collaborating directly with our client’s internal teams or their third-party CROs.
Who: Big Pharma
Where: Europe
Goal: Synthesis of diazaspiro derivatives with novel substitutions and exit vectors (5g scale)
SpiroChem assigned one chemist on FTE-based contract for 6 weeks
Development of a 9 step synthesis
Successful application of flow chemistry (H-cube technology)
Validation of the synthesis at 5g scale
Sustainable route for the preparation of additional diversified analogs
Who: Animal Health Care Company
Where: US
Goal: Design and synthesis of novel 3D spiro scaffolds
SpiroChem assigned one chemist on FTE-based contract for 4 months
Development of a 8 step synthesis
Introduction of diversified protecting groups for highest versatility
Validation of the synthesis at 10g scale
Outcome : US patent application